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Transplantation ; 105(4): 861-866, 2021 04 01.
Article in English | MEDLINE | ID: covidwho-1148015

ABSTRACT

BACKGROUND: Regional variation in lung transplantation practices due to local coronavirus disease 2019 (COVID-19) prevalence may cause geographic disparities in access to lung transplantation. METHODS: Using the United Network for Organ Sharing registry, we conducted a descriptive analysis of lung transplant volume, donor lung volume, new waitlist activations, and waiting list deaths at high-volume lung transplant centers during the first 3 months of the pandemic (March 1. 2020, to May 30, 2020) and we compared it to the same period in the preceding 5 years. RESULTS: Lung transplant volume decreased by 10% nationally and by a median of 50% in high COVID-19 prevalence centers (range -87% to 80%) compared with a median increase of 10% (range -87% to 80%) in low prevalence centers (P-for-trend 0.006). Donation services areas with high COVID-19 prevalence experienced a greater decrease in organ availability (-28% range, -72% to -11%) compared with low prevalence areas (+7%, range -20% to + 55%, P-for-trend 0.001). Waiting list activations decreased at 18 of 22 centers. Waiting list deaths were similar to the preceding 5 years and independent of local COVID-19 prevalence (P-for-trend 0.36). CONCLUSIONS: Regional variation in transplantation and donor availability in the early months of the pandemic varied by local COVID-19 activity.


Subject(s)
COVID-19/epidemiology , Lung Transplantation , Pandemics , SARS-CoV-2 , Tissue and Organ Procurement , Adult , Aged , Cohort Studies , Female , Humans , Lung Transplantation/statistics & numerical data , Lung Transplantation/trends , Male , Middle Aged , Prevalence , Registries/statistics & numerical data , Retrospective Studies , Tissue Donors/statistics & numerical data , Tissue Donors/supply & distribution , Tissue and Organ Procurement/statistics & numerical data , Tissue and Organ Procurement/trends , United States/epidemiology , Waiting Lists/mortality , Young Adult
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